When you hear herpes zoster ophthalmicus (HZO), the word herpes might catch your attention—but this condition is all about eye health, not STIs. Here’s what you need to know about HZO, including how to manage it.

What Is Herpes Zoster Ophthalmicus?

Herpes zoster ophthalmicus is a viral infection targeting the eye as well as the surrounding area and the upper part of the face. Cases of HZO are relatively low, with medical research showing that 30.9 out of 100,000 people in the U.S. will develop the condition. It most often occurs after the age of 50.

Causes

How do you get herpes zoster ophthalmicus? It’s caused by the same virus that triggers chickenpox—the varicella-zoster virus. After you have chickenpox, the virus can remain dormant in your body and reactivate later in life as shingles. In the case of HZO, it reactivates in the ophthalmic branch of the trigeminal nerve, which supplies sensation to the eye and forehead.

Aging, a weakened immune system, or stress can reactivate the virus. When reactivated, the virus moves along the nerve to the eye, causing inflammation and various symptoms.

Symptoms

The symptoms of herpes zoster ophthalmicus usually begin with pain, tingling, or a burning sensation on one side of the face.

These initial symptoms may be followed by:

  • A rash or blisters around the eye, forehead, and sometimes the tip of the nose
  • Redness and swelling
  • Sensitivity to light, or photophobia
  • Blurred vision
  • Discharge from the eye

Various types of eye inflammation can develop, including:

  • Keratitis, or inflammation of the cornea
  • Uveitis, or inflammation of the uvea
  • Scleritis, or inflammation of the sclera
  • Conjunctivitis (pink eye), or inflammation of the conjunctiva

Without prompt treatment, HZO can cause serious issues like corneal ulcers or even vision loss.

Diagnosis

To determine if you have herpes zoster ophthalmicus, you’ll need an eye exam. Your eye doctor may be able to verify the condition if you have the characteristic rash and blisters around your eye and forehead.

If your doctor has concerns about vision complications, they may conduct tests to assess the extent of eye involvement. They may check your eye pressure and examine your cornea for signs of inflammation. Additional tests, like culture or polymerase chain reaction (PCR) studies, are only done when lesions are unusual and the diagnosis is unclear.

Treatment Options

Wondering how to treat herpes zoster ophthalmicus? The main goal is to reduce pain, manage symptoms, and prevent complications. Doctors typically prescribe antiviral medications (e.g., acyclovir, famciclovir, or valacyclovir) to help shorten the duration of the outbreak and lessen its severity.

Pain relievers and corticosteroids may also reduce inflammation and discomfort. More intensive treatments might be necessary in severe cases, especially if the cornea is affected.

If you think you might have herpes zoster ophthalmicus or have any other vision health concerns, schedule an eye exam with Visionworks today!

Frequently Asked Questions